anti-2009H1N1 antibody product blog
Tags: Antibody; Monoclonal Antibody; 2009H1N1; anti-2009H1N1 antibody;
The 2009H1N1 m (Catalog #MBS845904) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-2009H1N1 monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s 2009H1N1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA); Immunohistochemistry (IHC).ELISA: 1-5 ug/ml (Detection sensitivity-10 ng/ml)
Immunocytochemistry: 5-10 ug/ml. Researchers should empirically determine the suitability of the 2009H1N1 m for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The 2009H1N1 m product has the following accession number(s) (GI #138819) (NCBI Accession #P05777.2) (Uniprot Accession #P05777). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Monoclonal antibody to detect H1N1 in human samples.
Plays critical roles in virus replication; from virus entry and uncoating to assembly and budding of the virus particle. M1 binding to ribonucleocapsids (RNPs) in nucleus seems to inhibit viral transcription. Interaction of viral NEP with M1-RNP is thought to promote nuclear export of the complex; which is targeted to the virion assembly site at the apical plasma membrane in polarized epithelial cells. Interactions with NA and HA may bring M1; a non-raft-associated protein; into lipid rafts. Forms a continuous shell on the inner side of the lipid bilayer in virion; where it binds the RNP. During virus entry into cell; the M2 ion channel acidifies the internal virion core; inducing M1 dissociation from the RNP. M1-free RNPs are transported to the nucleus; where viral transcription and replication can take place.
In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing 2009H1N1 are readily searchable from our website. Different antibodies against the same target such as 2009H1N1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. 2009H1N1 also interacts with the following gene(s): FLNA.