|The 26S Proteasome P52 Subunit n/a (Catalog #MBS831422) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The 26S Proteasome P52 Subunit antibody reacts with Rat, Kangaroo and may cross-react with other species as described in the data sheet. MyBioSource\'s 26S Proteasome P52 Subunit can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
WB: 1:5 - 1:10. Researchers should empirically determine the suitability of the 26S Proteasome P52 Subunit n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Mouse monoclonal 26S Proteasome P52 Subunit antibody.
Biological Significance: In eukaryotic cells, most proteins in the cytosol and nucleus are degraded via the ubiquitin-proteasome pathway. The 26S proteasome is a 2.5-MDa molecular machine built from approximately 31 different subunits, which catalyzes protein degradation. It contains a barrel-shaped proteolytic core complex (the 20S proteasome), capped at one or both ends by 19S regulatory complexes, which recognize ubiquitinated proteins. The regulatory complexes are also implicated in unfolding and translocation of ubiquitinated targets into the interior of the 20S complex, where they are degraded to oligopeptides. Immunogen: 26S Proteasome P52 Subunit antibody was raised in mouse using 26S proteasomes purified from Xenopus laevis ovary as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing 26S Proteasome P52 Subunit are readily searchable from our website. Different antibodies against the same target such as 26S Proteasome P52 Subunit may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.