|The ACE ace (Catalog #MBS601134) is an Antibody produced from Host: Mouse
Source: Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti - Angiotensin I Converting Enzyme-1 (ACE-1) reacts with Feline, Hamster, Human, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Angiotensin I Converting Enzyme-1 can be used in a range of immunoassay formats including, but not limited to, ELISA, Western Blot.
Suitable for use in ELISA and Western Blot. Other applications not tested.
Dilution: ELISA: 1:1000-1:10,000
Western Blot: 2-5ug/ml
Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the ACE ace for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ACE ace product has the following accession number(s) (GI #4503273) (NCBI Accession #NP_000780.1) (Uniprot Accession #P12821). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Renin-Angiotensin System (RAS) is a critical regulator of blood pressure homeostasis. The protease renin cleaves angiotensinogen into inactive decameric peptide angiotensin-I.
Immunogen: Purified human/rat lung ACE protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ACE are readily searchable from our website. Different antibodies against the same target such as ACE may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Brain, Eye, Heart, Intestine, Kidney, Lung, Muscle, Testis, Vascular tissues are correlated with this protein. ACE also interacts with the following gene(s): AGTR2, BDKRB2, COMT. Cardiomegaly, Cardiovascular Diseases, Coronary Artery Disease, Diabetes Mellitus, Type 2, Heart Failure, Hypertension, Kidney Diseases, Myocardial Infarction, Renal Insufficiency, Stroke are some of the diseases may be linked to Anti - Angiotensin I Converting Enzyme-1 (ACE-1).