anti-Actn antibody product blog
Tags: Antibody; Monoclonal Antibody; Alpha Actinin; Actn; anti-Actn antibody;
The Actn n/a (Catalog #MBS833611) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s alpha Actinin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Formalin/Paraffin.Optimal conditions to be determined by the end user. Researchers should empirically determine the suitability of the Actn n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Actn n/a product has the following accession number(s) (GI #442614871) (NCBI Accession #NP_001259167.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Mouse monoclonal alpha Actinin antibody.
Biological Significance: Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. Immunogen: alpha Actinin antibody was raised in mouse using Rabbit skeletal alpha-actinin as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Actn are readily searchable from our website. Different antibodies against the same target such as Actn may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.