anti-ACVRL1� antibody product blog
Tags: Antibody; Monoclonal Antibody; ACVRL1�; anti-ACVRL1� antibody;
The ACVRL1� acvrl1 (Catalog #MBS2543829) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Human�ACVRL1� Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s ACVRL1� can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP).WB: 2-10 mug/mL
IP: 1-4 uL/mg of lysate. Researchers should empirically determine the suitability of the ACVRL1� acvrl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ACVRL1� acvrl1 product has the following accession number(s) (GI #957948854). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. On ligand binding, a heteromeric receptor complex forms consisting of two type II and two type I transmembrane serine/threonine kinases. ACVRL1 protein is expressed in certain blood vessels of kidney, spleen, heart and intestine, serving as an important role during vascular development. Mutations in ACVRL1 gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2 and vascular disease.
Immunogen: Recombinant Human ALK-1/ACVRL1 protein
Buffer: 0.2 mum filtered solution in PBS with 5% trehalose. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ACVRL1� are readily searchable from our website. Different antibodies against the same target such as ACVRL1� may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. ACVRL1� also interacts with the following gene(s): ACVR2A, ACVR2B, ENG, SMAD1, SMAD5, SMAD9, TGFB1, TGFB3, TGFBR2. Breast Neoplasms, Cardiovascular Diseases, Fibrosis, Heart Diseases, Hypertension, Inflammation, Liver Diseases, Lung Diseases, Lung Neoplasms, Telangiectasia, Hereditary Hemorrhagic are some of the diseases may be linked to Rabbit anti Human�ACVRL1� Monoclonal Antibody. Bone, Brain, Connective Tissue, Heart, Liver, Lung, Muscle, Skin, Umbilical Cord, Vascular tissues are correlated with this protein.