|The Adam22 adam22 (Catalog #MBS803418) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ADAM22 (cytoplasmic) Antibody reacts with Human (weak), Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s ADAM22 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC).
WB: 1ug/mL, IHC/ICC: 0.1-1.0ug/mL (Perox), 1.0-10ug/mL (IF). Researchers should empirically determine the suitability of the Adam22 adam22 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Adam22 adam22 product has the following accession number(s) (NCBI Accession #NP_01007221.1) (Uniprot Accession #Q9R1V6). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ADAM22 (cytoplasmic) Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Rat brain membrane lysate showing detection of ADAM22 protein using Mouse Anti-ADAM22 Monoclonal Antibody, Clone S46-30. Primary Antibody: Mouse Anti-ADAM22 Monoclonal Antibody at 1:100.)
Background Info: Detects ~90kDa.
Scientific Background: ADAM 22 belongs to the ADAM gene family which havebeen shown to bind integrin and therefore may have a part in cell to cell or cell to matrix interactions. ADAM 22 is unique in the fact that it is only observed in the nervous system and predominantly in the brain. ADAM 22 is attached by cytoskeletal scaffolds to the postsynaptic density and is a receptor for LGI1.
Certificate of Analysis: 1 ug/mL was sufficient for detection ofADAM22 in 10ug of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Adam22 are readily searchable from our website. Different antibodies against the same target such as Adam22 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.