anti-ADCK3 antibody product blog
Tags: Antibody; Monoclonal Antibody; CABC1; anti-ADCK3 antibody; ADCK3;
The ADCK3 adck3 (Catalog #MBS6012748) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CABC1 (ADCK3, CABC1, Chaperone activity of bc1 complex-like, mitochondrial, aarF domain-containing protein kinase 3) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CABC1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunofluorescence (IF).Suitable for use in Western Blot, Immunofluorescence, ELISA.
Dilution: ELISA: 1:1000
Western Blot: 1:100~250
Immunofluorescence: 1:10~50. Researchers should empirically determine the suitability of the ADCK3 adck3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ADCK3 adck3 product has the following accession number(s) (GI #34147522) (NCBI Accession #NP_064632.2) (Uniprot Accession #Q8NI60). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CABC1 (ADCK3, CABC1, Chaperone activity of bc1 complex-like, mitochondrial, aarF domain-containing protein kinase 3) with the following immunoassay(s):
Western Blot (WB) (CABC1 antibody western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CABC1 antibody detected the CABC1 protein (arrow).)
Immunofluorescence (IF) (Confocal immunofluorescent analysis of CABC1 Antibody with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green). DAPI was used to stain the cell nuclear (blue).)
This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined.
Immunogen: CABC1 Mab is generated from mouse immunized with CABC1 recombinant protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ADCK3 are readily searchable from our website. Different antibodies against the same target such as ADCK3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain Diseases, Kidney Diseases, Nervous System Diseases, Seizures, Tremor are some of the diseases may be linked to CABC1 (ADCK3, CABC1, Chaperone activity of bc1 complex-like, mitochondrial, aarF domain-containing protein kinase 3).