anti-AGT antibody product blog
Tags: Antibody; AGT; Monoclonal Antibody; anti-AGT antibody;
The AGT mgmt (Catalog #MBS9602349) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The AGT Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s AGT can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA).ELISA: 1:10000
WB: 1:500-1:2000
IF/ICC: 1:100-1:500. Researchers should empirically determine the suitability of the AGT mgmt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The AGT mgmt product has the following accession number(s) (GI #530394832) (NCBI Accession #XP_005252739.1) (Uniprot Accession #P16455). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the AGT Antibody with the following immunoassay(s):
Western Blot (WB) (Figure 1: Western blot analysis using AGT mouse mAb against human plasma (1).)
Description: AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II.
Function: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Similarity: Belongs to the MGMT family.
Immunogen: Purified recombinant fragment of human AGT expressed in E. Coli
Subcellular Location: Nucleus. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing AGT are readily searchable from our website. Different antibodies against the same target such as AGT may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. AGT also interacts with the following gene(s): CDKN2A, DNMT3B, ESR1, MLH1, MSH2, PTEN, RASSF1, TP53. Blood, Bone, Brain, Intestine, Liver, Lung, Lymph, Skin, Stomach, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene. Adenocarcinoma, Brain Neoplasms, Carcinoma, Carcinoma, Squamous Cell, Glioblastoma, Glioma, Lung Neoplasms, Neoplasms, Experimental, Nervous System Diseases, Recurrence are some of the diseases may be linked to AGT Antibody.