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anti-Ahsa1 antibody product blog

Posted on 2016-01-27 02:35:25 by mybiosource_staff
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Tags: Antibody; Monoclonal Antibody; AHA1; AHSA1; anti-AHSA1 antibody;
The Ahsa1 ahsa1 (Catalog #MBS802328) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Aha1 Antibody: ATTO 655 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Aha1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF).
1:1000 (WB). Researchers should empirically determine the suitability of the Ahsa1 ahsa1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The Ahsa1 ahsa1 product has the following accession number(s) (GI #22122515) (NCBI Accession #NP_666148.1) (Uniprot Accession #Q8BK64). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Aha1 Antibody: ATTO 655 with the following immunoassay(s):
Testing Data (IP of Aha1 tested on HeLa cell lysates.)
Testing Data Ahsa1.

Testing Data #2 (IF of Aha1 tested on HeLa cell lysates.)
Testing Data #2 Ahsa1.

Testing Data #3 (Western blot analysis of Aha1 in a human cell line mix, using a 1:1000 dilution.)
Testing Data #3 Ahsa1.

Background Info: Detects ~38kDa. Can run up to 45kDa on SDS Page

Scientific Background: Aha1 is a member of the Hsp90 cochaperone family, and is thought to stimulate Hsp90 ATPase activity by competing with p23 and other co-chaperones for Hsp90 binding (1, 2). It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/Hsp90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) (3). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors (4).

Conjugate: ATTO 655. Storage Buffer: 0.02M potassium phosphate, 0.15M sodium chloride, pH7.2. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Ahsa1 are readily searchable from our website. Different antibodies against the same target such as Ahsa1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Congenital Abnormalities, Fibrosis, Kidney Diseases, Lung Diseases, Nervous System Diseases are some of the diseases may be linked to Aha1 Antibody: ATTO 655. Kidney, Lung, Muscle, Spleen tissues are correlated with this protein.
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