anti-AID antibody product blog
Tags: Antibody; Monoclonal Antibody; AID; anti-AID antibody;
The AID n/a (Catalog #MBS837837) is an Antibody produced from Sheep and is intended for research purposes only. The product is available for immediate purchase. The AID antibody (biotin) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s AID can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Immunohistochemistry (IHC) Formalin, Western Blot (WB). Researchers should empirically determine the suitability of the AID n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the AID antibody (biotin) with the following immunoassay(s):
Immunofluorescence (IF) (Immunofluorescent staining of AID knock-out (top) or wild type (bottom) mouse intestinal Peyer\'s patches with AID antibody (MBS837837))
Immunofluorescence (IF) (Immunofluorescent staining of AID knock-out (top) or wild type (bottom) mouse intestinal Peyer\'s patches with AID antibody (MBS837837))
Rat monoclonal AID antibody (biotin).
Biological Significance: AID is a 24 kDa RNA-editing enzyme that converts cytosine into uracil. It plays a critical role during B cell development, specifically in somatic hypermutation (SHM) and immunoglobulin class switch recombination (CSR). Changes in levels of AID expression typically present with disease. For example, mutations in AID are found in Hyper-IgM Syndrome (type 2), a disease form without opportunistic infections, while overexpression correlates with poor prognosis in chronic lymphocytic leukemia/small lymphocytic lymphoma. Cross-Reactivity: Human, Mouse
Tag/Conjugate: Biotin. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing AID are readily searchable from our website. Different antibodies against the same target such as AID may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.