anti-Amyloid P Component, Serum antibody product blog
Tags: Antibody; Monoclonal Antibody; amyloid P component, serum; anti-Amyloid P Component, Serum antibody;
The Amyloid P Component, Serum n/a (Catalog #MBS631735) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Amyloid P Component, Serum, Human (SAP, APCS, PTX2, mature chain 204aa, chromosome 1q21-23) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Amyloid P Component, Serum can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:500-1:20,000
Western Blot: 1:500-1:5000. Researchers should empirically determine the suitability of the Amyloid P Component, Serum n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Amyloid P Component, Serum n/a product has the following accession number(s) (GI #294634). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Serum amyloid P component or SAP or APCS, or PTX2 (mature chain 204 aa, chromosome 1q21-23) with which CRP has about 59% homology, is situated in the same area of chromosome 1. SAP is universally present in amyloid deposits 9senile plaque and neurofibrially tangels) in Alzheimers patients. SAP levels in CSF can be useful for assessing cognitive impairment in AD patients. However, SAP appeared not to be required for A-beta deposition since no endogenous SAP immunoreactivity was found in mice overexpressing APP.
Immunogen: Human SAP purified from acute phase serum. Native form ~235kD. Monomer ~25kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Amyloid P Component, Serum are readily searchable from our website. Different antibodies against the same target such as Amyloid P Component, Serum may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Amyloid P Component, Serum also interacts with the following gene(s): FLNA. Bone, Brain, Connective Tissue, Ear, Embryonic Tissue, Heart, Kidney, Muscle, Umbilical Cord, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene.