anti-ANPEP antibody product blog
Tags: Antibody; Monoclonal Antibody; ANPEP; anti-ANPEP antibody;
The ANPEP anpep (Catalog #MBS9200489) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ANPEP Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s ANPEP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).WB~~1:100~500. Researchers should empirically determine the suitability of the ANPEP anpep for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ANPEP anpep product has the following accession number(s) (GI #157266300) (NCBI Accession #NP_001141.2) (Uniprot Accession #P15144). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ANPEP Antibody with the following immunoassay(s):
Western Blot (WB) (ANPEP Antibody western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the ANPEP antibody detected the ANPEP protein (arrow).)
Aminopeptidase N is located in the small-intestinal and
renal microvillar membrane, and also in other plasma membranes. In
the small intestine aminopeptidase N plays a role in the final
digestion of peptides generated from hydrolysis of proteins by
gastric and pancreatic proteases. Its function in proximal tubular
epithelial cells and other cell types is less clear. The large
extracellular carboxyterminal domain contains a pentapeptide
consensus sequence characteristic of members of the zinc-binding
metalloproteinase superfamily. Sequence comparisons with known
enzymes of this class showed that CD13 and aminopeptidase N are
identical. The latter enzyme was thought to be involved in the
metabolism of regulatory peptides by diverse cell types, including
small intestinal and renal tubular epithelial cells, macrophages,
granulocytes, and synaptic membranes from the CNS. Human
aminopeptidase N is a receptor for one strain of human coronavirus
that is an important cause of upper respiratory tract infections.
Defects in this gene appear to be a cause of various types of
leukemia or lymphoma.
Antigen Type: Recombinant Protein. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ANPEP are readily searchable from our website. Different antibodies against the same target such as ANPEP may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. ANPEP also interacts with the following gene(s): ENPEP. The following patways have been known to be associated with this gene.