anti-APP antibody product blog
Tags: Antibody; Monoclonal Antibody; APP; anti-APP antibody;
The APP app (Catalog #MBS531041) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The APP antibody reacts with To be determined by end-user and may cross-react with other species as described in the data sheet. MyBioSource\'s APP can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the APP app for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The APP app product has the following accession number(s) (GI #236721) (NCBI Accession #AAB19991.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Mouse monoclonal APP antibody.
Biological Significance: Amyloid precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. Its primary function is not known, though it has been implicated as a regulator of synapse formation, neural plasticity and iron export. APP is best known and most commonly studied as the precursor molecule whose proteolysis generates beta amyloid (ABeta), a 39- to 42-amino acid peptide whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer\'s disease patients. Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.
Immunogen: APP antibody was raised in mouse using prokaryotic recombinant fusion protein corresponding to the extra-cellular portion of APP between the Kunitz protease inhibitor domain and the beta -amyloid region as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing APP are readily searchable from our website. Different antibodies against the same target such as APP may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Alzheimer Disease, Amyloidosis, Brain Diseases, Dementia, Disease Models, Animal, Inflammation, Memory Disorders, Nervous System Diseases, Neurodegenerative Diseases, Plaque, Amyloid are some of the diseases may be linked to APP antibody. Blood, Brain, Heart, Intestine, Kidney, Liver, Lung, Muscle, Nerve, Vascular tissues are correlated with this protein.