anti-APP antibody product blog
Tags: Antibody; Monoclonal Antibody; APP; anti-APP antibody; Amyloid Beta A4 Precursor;
The APP app (Catalog #MBS838748) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Amyloid Beta A4 Precursor can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).WB: 1:500-1:1,000. Researchers should empirically determine the suitability of the APP app for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The APP app product has the following accession number(s) (GI #4502167) (NCBI Accession #NP_000475.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Amyloid Beta A4 Precursor antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis on hela cell lysates using anti-APP monoclonal antibody)
Mouse monoclonal Amyloid Beta A4 Precursor antibody.
Biological Significance: Amyloid Beta A4 Precursor is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Immunogen: Amyloid Beta A4 Precursor antibody was raised in Mouse using a synthetic peptide (KLH-coupled) corresponding to near C-terminal residues of APP as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing APP are readily searchable from our website. Different antibodies against the same target such as APP may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Alzheimer Disease, Amyloidosis, Brain Diseases, Dementia, Disease Models, Animal, Inflammation, Memory Disorders, Nervous System Diseases, Neurodegenerative Diseases, Plaque, Amyloid are some of the diseases may be linked to Amyloid Beta A4 Precursor antibody. The following patways have been known to be associated with this gene. Blood, Brain, Heart, Intestine, Kidney, Liver, Lung, Muscle, Nerve, Vascular tissues are correlated with this protein.