anti-ATIC antibody product blog
Tags: Antibody; Monoclonal Antibody; ATIC; anti-ATIC antibody;
The ATIC atic (Catalog #MBS475147) is an Antibody produced from MouseSource: Human and is intended for research purposes only. The product is available for immediate purchase. The Anti-ATIC Mouse mAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s ATIC can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
WB: 1:1000. Researchers should empirically determine the suitability of the ATIC atic for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ATIC atic product has the following accession number(s) (GI #20127454) (NCBI Accession #NP_004035.2) (Uniprot Accession #P31939). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-ATIC Mouse mAb with the following immunoassay(s):
Western Blot (WB) (Western blot detection of ATIC in various tissues and cell lysates using ATIC mouse mAb (1:1000 diluted).Predicted band size:64KDa.Observed band size:64KDa.)
Entrez Summary: This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.
UniPort Summary Function: Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis.
Immunogen: Purified recombinant human ATIC protein fragments expressed in E Coli.
Sensitivity: This antibody detects endogenous levels of ATIC and does not cross-react with related proteins.
Sequence Similarities: Belongs to the PurH family. Subunit Structure: Homodimer. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ATIC are readily searchable from our website. Different antibodies against the same target such as ATIC may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Arthritis, Rheumatoid, Carcinoma, Cell Transformation, Neoplastic, Drug Toxicity, Hypertension, Inflammation, Lung Neoplasms, Lymphoma, Renal Insufficiency, Translocation, Genetic are some of the diseases may be linked to Anti-ATIC Mouse mAb. Bladder, Blood, Bone, Kidney, Liver, Lung, Muscle, Ovary, Skin, Vascular tissues are correlated with this protein.