anti-Bad antibody product blog
Tags: Antibody; anti-BAD antibody; BAD; Monoclonal Antibody;
The Bad n/a (Catalog #MBS632026) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Bad, phosphorylated (Ser155) (Bcl-associated Death Promoter, Bcl2 Antagonist Of Cell Death, mBAD, Bcl-2-binding Component 6, Bcl-xL/Bcl-2-associated Death Promoter, Bbc6) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Bad can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500. Researchers should empirically determine the suitability of the Bad n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Bad, phosphorylated (Ser155) (Bcl-associated Death Promoter, Bcl2 Antagonist Of Cell Death, mBAD, Bcl-2-binding Component 6, Bcl-xL/Bcl-2-associated Death Promoter, Bbc6) with the following immunoassay(s):
Western Blot (WB) (Western analysis of cell extracts from 293 cells transfected with DYKDDDDK-Bad, using Phospho-mBad-Ser155.)
Apoptosis is a critical aspect of cellular function and is implicated in a broad range of human diseases, from cancer to neurodegenerative and cardiovascular diseases. Intrafamilial Bcl-2 protein contacts are thought to regulate key aspects of apoptosis. The corruption of apoptotic instructions is associated with a large subset of human diseases, ranging from cancer and cardiovascular disease to neurodegenerative diseases, and name just a few. Understanding regulation of apoptosis is necessary to constructing a strategy for pharmaceutical intervention. The BH3 domain of Bcl-2 family members has been identified as key to the Bcl-2 regulatory function, although details are not fully elucidated.
Immunogen: Synthetic phosphopeptide corresponding to sequences in Ser155 region of mouse Bad (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Bad are readily searchable from our website. Different antibodies against the same target such as Bad may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.