anti-Bcl-XL antibody product blog
Tags: Antibody; anti-BCL-XL antibody; BCL-XL; Monoclonal Antibody;
The BCL-x bcl2l1 (Catalog #MBS2540160) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The BCL-x Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s BCL-x can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA).WB: 1:2000-1:20000
IHC: 1:20-1:200
IF: 1:10-1:100. Researchers should empirically determine the suitability of the BCL-x bcl2l1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The BCL-x bcl2l1 product has the following accession number(s) (GI #4502381) (NCBI Accession #NP_001182.1) (Uniprot Accession #Q07817). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the BCL-x Monoclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Raw 264.7 cells using Bcl-XL Monoclonal Antibody at dilution of 1:20000)
BCL2L1 is a member of he BCL-2 protein family. BCL2L1 is expressed as two distinct isoforms, Bcl-xL and Bcl-xS, and is located at the outer mitochondrial membrane. The Bcl-XL isoform is a 233 amino acid protein, acting as an apoptotic inhibitor. Bcl-XL can forms heterodimers with BAX, BAK or BCL2, and the heterodimerization with BAX does not seem to be required for anti-apoptotic activity. The Bcl-XS isoform is a shorter variant that is 178 amino acids in length and lacks a 63 amino acid region (amino acids 126-188), acting as an apoptotic activator.
Immunogen: Fusion protein of Bcl-XL. Buffer: PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation: Unconjugated. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing BCL-x are readily searchable from our website. Different antibodies against the same target such as BCL-x may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Brain, Heart, Kidney, Liver, Lung, Muscle, Prostate, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene. Brain Diseases, Breast Neoplasms, Carcinoma, Drug Toxicity, Gastrointestinal Diseases, Liver Diseases, Necrosis, Neoplasms, Neoplasms, Experimental, Nervous System Diseases are some of the diseases may be linked to BCL-x Monoclonal Antibody.