|The BDNF bdnf (Catalog #MBS2542129) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The BDNF Monoclonal Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s BDNF can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF), ELISA (EIA).
IF: 1:50-1:500. Researchers should empirically determine the suitability of the BDNF bdnf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The BDNF bdnf product has the following accession number(s) (GI #219842288) (NCBI Accession #NP_001137277.1) (Uniprot Accession #P23560). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the BDNF Monoclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of U-251 cells using BDNF Monoclonal Antibody at dilution of 1:1000)
BDNF is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of BDNF is reduced in both Alzheimer\'s and Huntington disease patients. It play a role in the regulation of stress response and in the biology of mood disorders.
Immunogen: Fusion protein of BDNF. Buffer: PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation: Unconjugated. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing BDNF are readily searchable from our website. Different antibodies against the same target such as BDNF may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Body Weight, Brain Injuries, Brain Ischemia, Cognition Disorders, Depressive Disorder, Inflammation, Memory Disorders, Movement Disorders, Nervous System Diseases, Schizophrenia are some of the diseases may be linked to BDNF Monoclonal Antibody. Adrenal Gland, Brain, Connective Tissue, Embryonic Tissue, Eye, Heart, Liver, Lung, Skin, Thyroid tissues are correlated with this protein. BDNF also interacts with the following gene(s): CDC42, CREB1, NGFR, NTF3, NTF4, NTRK1, NTRK2, NTRK3, PLCG1, SORT1. The following patways have been known to be associated with this gene.