anti-BECN1 antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-BECN1 antibody; BECN1;
The BECN1 becn1 (Catalog #MBS857946) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The BECN1 (Beclin 1) Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s BECN1 (Beclin 1) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the BECN1 becn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The BECN1 becn1 product has the following accession number(s) (GI #929524267) (NCBI Accession #NP_001300927.1) (Uniprot Accession #Q14457). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the BECN1 (Beclin 1) Antibody with the following immunoassay(s):
Testing Data (Western blot detection of BECN1 in Mouse brain,A431&Hela cell lysates using BECN1 antibody (1:1000 diluted). Predicted band size:52KDa. Observed band size:55KDa.)
UniPort Summary Function: Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.
Entrez Summary: Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 [PubMed 19270693]).
Immunogen: Purified recombinant human BECN1 protein fragments expressed in E Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing BECN1 are readily searchable from our website. Different antibodies against the same target such as BECN1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Carcinoma, Hepatocellular, Cardiovascular Diseases, Disease Models, Animal, Heart Diseases, Inflammation, Liver Diseases, Lung Neoplasms, Necrosis, Neoplasm Metastasis, Nervous System Diseases are some of the diseases may be linked to BECN1 (Beclin 1) Antibody. BECN1 also interacts with the following gene(s): AMBRA1, ATG14, BCL2, BCL2L1, MCL1, PARK2, PIK3C3, PIK3R4, UVRAG. Blood, Bone, Brain, Heart, Kidney, Liver, Lung, Muscle, Nerve, Vascular tissues are correlated with this protein.