anti-BMI1 antibody product blog
Tags: Antibody; Monoclonal Antibody; BMI1; anti-BMI1 antibody;
The BMI1 n/a (Catalog #MBS476229) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-BMI1 Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s BMI1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the BMI1 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The BMI1 n/a product has the following accession number(s) (GI #525345323) (NCBI Accession #NP_001266761.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-BMI1 Mouse mAb with the following immunoassay(s):
Western Blot (WB) (Western blot analysis using BMI1 mAb against human BMI1 (AA)
Western Blot (WB) (Western blot analysis using BMI1 mAb against HEK293 (1) and BMI1-hIgGFc transfected HEK293 (2) cell lysate.)
Immunofluorescence (IF) (Immunofluorescence analysis of Hela cells using BMI1 mouse mAb (green). Blue)
Flow Cytometry (FC/FACS) (Flow cytometric analysis of NIH/3T3 cells using BMI1 mouse mAb (green) and negative control (red).)
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using BMI1 mouse mAb with DAB staining.)
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using BMI1 mouse mAb with DAB staining.)
Entrez Summary: Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A \'Lys-119\', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Immunogen: Purified recombinant fragment of human BMI1 expressed in E Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing BMI1 are readily searchable from our website. Different antibodies against the same target such as BMI1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.