|The BMP-10 bmp10 (Catalog #MBS690400) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Human BMP-10 reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s BMP-10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Neutr. Researchers should empirically determine the suitability of the BMP-10 bmp10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The BMP-10 bmp10 product has the following accession number(s) (GI #7656928) (NCBI Accession #NP_055297.1) (Uniprot Accession #O95393). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Bone morphogenetic protein 10 (BMP10) is a TGFbeta superfamily member whose expression is restricted to the developing and postnatal heart. It is synthesized as a 424 amino acid (aa) preproprotein with a putative 21 aa signal peptide, a 295 aa propeptide, and a 108 aa mature protein. Mature BMP10 is secreted as a 25 kDa disulfidelinked homodimer. Mature human BMP10 shares 98% aa sequence identity with mature mouse, and rat BMP10.
Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of Bone Morphogenetic Protein 10 (BMP-10). Reconstitution: Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing BMP-10 are readily searchable from our website. Different antibodies against the same target such as BMP-10 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Dysostoses, Fibrosis, Inflammation, Necrosis, Neoplasm Metastasis, Vascular Malformations are some of the diseases may be linked to Mouse Anti-Human BMP-10. BMP-10 also interacts with the following gene(s): ACVRL1, ATF3, CDKN1C, MYH6, PARP1, SMARCA4, TBX20. The following patways have been known to be associated with this gene.