anti-BTN2A1 antibody product blog
Tags: Antibody; Monoclonal Antibody; BTN2A1; anti-BTN2A1 antibody;
The BTN2A1 btn2a1 (Catalog #MBS645339) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The BTN2A1 (Butyrophilin Subfamily 2 Member A1, BT2.1, BTF1) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s BTN2A1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA).Suitable for use in ELISA.
Dilution: Sandwich ELISA: The detection limit for recombinant GST tagged BTN2A1 is ~1ng/ml as a capture antibody. Researchers should empirically determine the suitability of the BTN2A1 btn2a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The BTN2A1 btn2a1 product has the following accession number(s) (GI #308522730) (NCBI Accession #NP_001184163.1) (Uniprot Accession #Q7KYR7). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MESAAALHFS RPASLLLLLL SLCALVSAQF IVVGPTDPIL ATVGENTTLR CHLSPEKNAE DMEVRWFRSQ FSPAVFVYKG GRERTEEQME EYRGRTTFVS KDISRGSVAL VIHNITAQEN GTYRCYFQEG RSYDEAILHL VVAGLGSKPL ISMRGHEDGG IRLECISRGW YPKPLTVWRD PYGGVAPALK EVSMPDADGL FMVTTAVIIR DKSVRNMSCS INNTLLGQKK ESVIFIPESF MPSVSPCAVA LPIIVVILMI PIAVCIYWIN KLQKEKKILS GEKEFERETR EIALKELEKE RVQKEEELQV KEKLQEELRW RRTFLHAELQ FFSN.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the BTN2A1 (Butyrophilin Subfamily 2 Member A1, BT2.1, BTF1) with the following immunoassay(s):
Testing Data (Detection limit for recombinant GST tagged BTN2A1 is ~1ng/ml using MBS645339 as a capture antibody.)
The MHC-encoded butyrophilin, BTN2A1, is a cell surface glycoprotein related to the extended family of B7 costimulatory molecules. BTN2A1 mRNA is expressed in most human tissues, but protein expression is significantly lower in leukocytes. The protein is an integral plasma membrane B box protein involved in lipid, fatty-acid and sterol metabolism. Recent studies reveal that the protein can negatively regulate T cell proliferation and cytokine production. Additionally, genetic studies have described polymorphisms in the protein which are reported to be associated with disorders such as sarcoidosis, myositis andulcerative colitis. Human BTN2A1 gene is located in 6p22.1.
Immunogen: Full length recombinant corresponding to aa1-335 from human BTN2A1 (AAH16661) with GST tag. MW of the GST tag alone is 26kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing BTN2A1 are readily searchable from our website. Different antibodies against the same target such as BTN2A1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.