Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource  rightarrow Monoclonal Antibody Blog  rightarrow anti-C2  antibody  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Blogs moreseparator
 • anti-GnRH, LHRH antibody blog
 • anti-APIP antibody blog
 • anti-CKB antibody blog
 • anti-CD40 antibody blog
 • anti-Slc17a8 antibody blog
 • anti-GSS antibody blog
 • anti-PAX-8 antibody blog
 • anti-CD45 antibody blog
 • anti-CDC27 antibody blog
 • anti-Ly-6G/GR-1 antibody blog
 • anti-HSP90B1 antibody blog
 • anti-CDCP1 antibody blog
 • anti-MC1R antibody blog
 • anti-CD25 antibody blog
 • anti-LCK antibody blog
 • anti-beta-actin antibody blog
 • anti-SIGLEC10 antibody blog
 • anti-PCSK9 antibody blog
 • anti-CD45 antibody blog
 • anti-LMNB1 antibody blog
Blog Categories separator
 • Assay Kit Blogs
 • Biochemical Blogs
 • cDNA Clone Blogs
 • Monoclonal Antibody Blogs
 • Polyclonal Antibody Blogs
 • Rec/Purified Protein Blogs
 • Popular Product Blogs
Our Best Sellers moreseparator
 • Cotinine 3 Antibody
 • CEA Native Protein
 • HLA-ABC Antibody
 • Dact3 Antibody
 • Calpain-1 catalytic subunit (Capn1) Recombinant Protein
 • Donkey Anti-Mouse IgG (H+L) Secondary Antibody
 • diuretic hormone-vasopressin-arginin e vasopressin, ADH-VP-AV... ELISA Kit
 • Hydrochloric acid Biochemical
 • RECS1 Antibody
 • VEGF Antibody
 • S-phase Kinase-Associated Protein 1 Isoform A (SKP1) Recombinant Protein
 • prorenin-renin IgG fraction, HRP labeled Antibody
 • CD86 Antibody
 • beta Galactosidase (GLB1) Antibody
 downarrow more ...

anti-C2  antibody product blog

Posted on 2017-03-03 20:26:20 by mybiosource_staff
Share it on ...     
Tags: Antibody; Monoclonal Antibody; anti-C2  antibody;
The C2  c2 (Catalog #MBS2543863) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Human C2  Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s C2  can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA).
ELISA: 0.1-0.2 mug/mL. This antibody can be used at 0.1-0.2 mug/mL with the appropriate secondary reagents to detect Human C2. The detection limit for Human C2 is 0.0049 ng/well. Researchers should empirically determine the suitability of the C2  c2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The C2  c2 product has the following accession number(s) (GI #15277207). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Complement component C2 is part of the classical complement pathway which plays a major role in innate immunity against infection. C2 is a glycoprotein synthesized in liver hepatocytes and several other cell types in extrahepatic tissues. This pathway is triggered by a multimolecular complex C1, and subsequently the single-chain form of C2 is cleaved into two chains referred to C2a and C2b by activated C1. The second component of complement (C2) is a multi-domain serine protease that provides catalytic activity for the C3 and C5 convertases of the classical and lectin pathways of human complement. C4b and C2 was investigated by surface plasmon resonance. C2a containing a serine protease domain combines with complement component C4b to form the C3 convertase C4b2a which is responsible for C3 activation, and leads to the stimulation of adaptive immune responses via Lectin pathway. C2 bound to C4b is cleaved by classical (C1s) or lectin (MASP2) proteases to produce C4bC2a. C2 has the same serine protease domain as C4bC2a but in an inactive zymogen-like conformation, requiring cofactor-induced conformational change for activity. Deficiency of C2 (C2D) is the most common genetic deficiency of the complement system, and two types of C2D have been recognized in the context of specific MHC haplotypes. C2D in human is reported to increase susceptibility to infection, and is associated with certain autoimmune diseases, such as rheumatological disorders.

C2  c2

Immunogen: Recombinant Human C2 protein
Buffer: This antibody was obtained from a rabbit immunized with purified, recombinant Human complement component 2 (rh C2; Met 1-Leu 752; NP_000054.2). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing C2  are readily searchable from our website. Different antibodies against the same target such as C2  may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions