anti-Cacna1g antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-Cacna1g antibody; Cacna1g; Cav3.1;
The Cacna1g cacna1g (Catalog #MBS804578) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CaV3.1 Antibody: ATTO 488 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s CaV3.1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).1:1000 (WB). Researchers should empirically determine the suitability of the Cacna1g cacna1g for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Cacna1g cacna1g product has the following accession number(s) (GI #163914404) (NCBI Accession #NP_001106284.1) (Uniprot Accession #Q9WUT2). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CaV3.1 Antibody: ATTO 488 with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Rat brain membrane lysate showing detection of Cav3.1 Calcium Channel protein using Mouse Anti-Cav3.1 Calcium Channel Monoclonal Antibody, Clone S178A-9. Primary Antibody: Mouse Anti-Cav3.1 Calcium Channel Monoclonal Antibody at 1:1000.)
Background Info: Detects ~>200kDa. Does not cross-react with Cav3.2
Scientific Background: Calcium channel CaV3.1 (a1G) is a low-voltage-activated T-type calcium channel. Such T-type channels are expressed throughout the body. In the heart, they may be involved in pacemaker current. In neurons, these channels may play a secondary pacemaker role (3). With the ubiquitous expression, it is not surprising that alterations in channel function have been implicated in disease. Drugs that act to block T-type calcium channels are used as anti-hypertensives, antiepileptic\'s, and blocking of T-type calcium channels may be involved in the action of some anesthetics and antipsychotics as well (3). Much remains to be determined about the precise cellular localization, in vivo physiological roles, roles in disease states and possible routes to modulate their structure/function to ameliorate effects of disease.
Conjugate: ATTO 488. Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Cacna1g are readily searchable from our website. Different antibodies against the same target such as Cacna1g may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Embryonic Tissue, Eye, Kidney, Liver, Lung, Pancreas, Pituitary Gland, Stomach, Uncharacterized Tissue tissues are correlated with this protein.