|The Cacng2 cacng2 (Catalog #MBS803084) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TARP Gamma2/4/8 (Stargazin)Antibody: Streptavidin reacts with Rat, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s TARP Gamma2/4/8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC).
1ug/mL (WB). Researchers should empirically determine the suitability of the Cacng2 cacng2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Cacng2 cacng2 product has the following accession number(s) (GI #16758072) (NCBI Accession #NP_445803.1) (Uniprot Accession #Q71RJ2). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TARP Gamma2/4/8 (Stargazin)Antibody: Streptavidin with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Rat brain lysates showing detection of Stargazin Calcium Channel protein using Mouse Anti-Stargazin Calcium Channel Monoclonal Antibody, Clone S245-36. Primary Antibody: Mouse Anti-Stargazin Calcium Channel Monoclonal Antibody at 1:100, 1:250, 1:500, and 1:1000.)
Background Info: Detects ~35-55kDa. Does not cross-react with TARPGamma3.
Scientific Background: Stargazin belongs to a group called voltage gated calcium channels (VGCCs) which are present in most excitable cells. Stargazin is thought to stabilize the calcium channel in an inactivated (closed) state. There are five high voltage activated calcium channel types (L, N, P, Q, and R) and one low voltage activated channel type (T). Each of these channels exists as a heteromultimer of a1, b, a2/ d and g subunits with the voltage activated calcium channel function carried by the a subunits. VGCCs exert spatial and temporal control over cellular calcium concentrations and serve to modulate neurotransmitter release, hormone secretion, muscle contraction, electrical activity, cell metabolism and proliferation, gene expression, and neuronal survival.
Conjugate: Streptavidin. Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Cacng2 are readily searchable from our website. Different antibodies against the same target such as Cacng2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.