anti-CALCA antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-CALCA antibody; CALCA; CALCA/CT;
The CALCA calca (Catalog #MBS647786) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CALCA/CT (CALCA, CALC1, Calcitonin, Katacalcin, Calcitonin carboxyl-terminal peptide, PDN-21) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CALCA/CT can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in Western Blot, ELISA.
Dilution: ELISA: 1:1,000
Western Blot: 1:100~250. Researchers should empirically determine the suitability of the CALCA calca for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CALCA calca product has the following accession number(s) (GI #76880484) (NCBI Accession #NP_001029124.1) (Uniprot Accession #P01258). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CALCA/CT (CALCA, CALC1, Calcitonin, Katacalcin, Calcitonin carboxyl-terminal peptide, PDN-21) with the following immunoassay(s):
Western Blot (WB) (CALCA/CT Antibody western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the CALCA/CT antibody detected the CALCA/CT protein (arrow).)
This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen: Purified His-tagged CALCA/CT protein (fragment). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CALCA are readily searchable from our website. Different antibodies against the same target such as CALCA may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CALCA also interacts with the following gene(s): ADM, CALCRL, IAPP, RAMP1. Edema, Headache, Hypercalcemia, Hypertension, Inflammation, Kidney Diseases, Migraine Disorders, Neurogenic Inflammation, Pain, Wounds and Injuries are some of the diseases may be linked to CALCA/CT (CALCA, CALC1, Calcitonin, Katacalcin, Calcitonin carboxyl-terminal peptide, PDN-21). Brain, Thyroid tissues are correlated with this protein. The following patways have been known to be associated with this gene.