anti-CASR antibody product blog
Tags: Antibody; anti-CASR antibody; CASR; Monoclonal Antibody; Calcium Sensing Receptor;
The CASR casr (Catalog #MBS603811) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Calcium Sensing Receptor (CASR) reacts with Human, Mouse, Rabbit, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Calcium Sensing Receptor can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).Suitable for use in Western Blot.
Dilution: Western Blot: 1:50-1:200 Recognizes a band at ~130kD and a large smear at the top of the gel. This protein is susceptible to aggregation, thus resulting in just seeing the high MW smear. Researchers should empirically determine the suitability of the CASR casr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CASR casr product has the following accession number(s) (GI #30171429) (Uniprot Accession #Q2F3K1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Calcium Sensing Receptor (CASR) with the following immunoassay(s):
Testing Data (Detection of Calcium Sensing Receptor in transfected 293 cell lysate using MBS603811. ECL exposure, 5 minutes. In this photo, the protein has aggregated and thus the higher MW band as expected.)
The calcium-sensing receptor (CaSR) is an integral membrane protein that is a member of the G protein-coupled receptor family. It senses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system.
Immunogen: N-tertminal, extracellular region of human Calcium Sensing Receptor. Cellular Localization: Cytoplasmic. Positive Control: Human Kidney Protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CASR are readily searchable from our website. Different antibodies against the same target such as CASR may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Eye, Kidney, Liver, Pancreas, Parathyroid tissues are correlated with this protein. The following patways have been known to be associated with this gene. Adenoma, Colorectal Neoplasms, Hypercalcemia, Hypercalciuria, Hyperparathyroidism, Hyperparathyroidism, Secondary, Hypertension, Kidney Diseases, Osteoporosis, Renal Insufficiency are some of the diseases may be linked to Calcium Sensing Receptor (CASR). CASR also interacts with the following gene(s): PRKCA.