|The CAT cat (Catalog #MBS9200119) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CAT Antibody (Center) (Ascites) reacts with Human, mouse (Predicted Reactivity: Bovine, Zebrafish, Pig, Rat) and may cross-react with other species as described in the data sheet. MyBioSource\'s CAT can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).
WB~~1:100~1600. Researchers should empirically determine the suitability of the CAT cat for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CAT cat product has the following accession number(s) (GI #4557014) (NCBI Accession #NP_001743.1) (Uniprot Accession #P04040). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CAT Antibody (Center) (Ascites) with the following immunoassay(s):
Western Blot (WB) (CAT Antibody (Center)(Ascites) western blot analysis in mouse Liver tissue lysates (35ug/lane).This demonstrates the CAT antibody detected the CAT protein (arrow).)
Western Blot (WB) (CAT Antibody (Center) (Ascites) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CAT antibody detected the CAT protein (arrow).)
This gene encodes catalase, a key antioxidant enzyme in
the bodies defense against oxidative stress. Catalase is a heme
enzyme that is present in the peroxisome of nearly all aerobic
cells. Catalase converts the reactive oxygen species hydrogen
peroxide to water and oxygen and thereby mitigates the toxic
effects of hydrogen peroxide. Oxidative stress is hypothesized to
play a role in the development of many chronic or late-onset
diseases such as diabetes, asthma, Alzheimer\'s disease, systemic
lupus erythematosus, rheumatoid arthritis, and cancers.
Polymorphisms in this gene have been associated with decreases in
catalase activity but, to date, acatalasemia is the only disease
known to be caused by this gene.
Antigen Type: Synthetic Peptide. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CAT are readily searchable from our website. Different antibodies against the same target such as CAT may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CAT also interacts with the following gene(s): AKT1, FOXO3, GSR, PEX5, SOD1, SOD2, SOD3, XDH. Blood, Brain, Eye, Heart, Kidney, Liver, Muscle, Nerve, Skin, Vascular tissues are correlated with this protein.