anti-CCL-15 antibody product blog
Tags: Antibody; Monoclonal Antibody; CCL-15; anti-CCL-15 antibody;
The CCL-15 ccl15 (Catalog #MBS690003) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Human CCL-15 reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CCL-15 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Neutr. Researchers should empirically determine the suitability of the CCL-15 ccl15 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The CCL-15 ccl15 product has the following accession number(s) (GI #14602449) (NCBI Accession #NP_116741.1) (Uniprot Accession #Q16663). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
CCL15, a human CC chemokine, was isolated from a human fetal spleen cDNA library. CCL15 cDNA encodes a predicted 113 amino acid (aa) protein containing a putative signal peptide of 21 aa that is cleaved to generate a 92 aa residue mature protein. Within the CC family members, human CCL15 shares 45%, 44%, 35%, and 30% aa homology with mouse C10, human MPIF1, human HCC1, and mouse MIP1gamma, respectively. The gene for MIP1delta is found on chromosome 17 where the genes for most of the human CC chemokines are located. Human CCL15 is expressed in T and B lymphocytes, NK cells, monocytes and monocytederived dendritic cells. Human MIP1delta is chemotactic for T cells and monocytes and has been shown to induce calcium flux in human CCR1transfected cells.
Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of CCL-15 (also called MIP-1d). Reconstitution: Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CCL-15 are readily searchable from our website. Different antibodies against the same target such as CCL-15 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Ascites, Brain, Intestine, Kidney, Liver, Lung tissues are correlated with this protein. CCL-15 also interacts with the following gene(s): CCR1, CCR2, CCR3, CCR5, CCR6, CCR7, CCR8. Adenocarcinoma, Carcinoma, Carcinoma, Hepatocellular, Inflammation, Kidney Diseases, Liver Diseases, Liver Neoplasms, Necrosis, Neoplasm Metastasis, Neoplasms are some of the diseases may be linked to Mouse Anti-Human CCL-15.