anti-CD10 antibody product blog
Tags: Antibody; Monoclonal Antibody; CD10; anti-CD10 antibody;
The CD10 n/a (Catalog #MBS833297) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s CD10 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS).FC: 5 ul (0.06 ug)/test
A test is defined as the amount (ug)/test of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Researchers should empirically determine the suitability of the CD10 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CD10 antibody (PE) with the following immunoassay(s):
Flow Cytometry (FC/FACS) (Staining of normal human peripheral blood cells with Mouse IgG1 kappa Isotype Control (PE) (blue histogram) or CD10 antibody (PE) (purple histogram).)
Mouse monoclonal CD10 antibody (PE).
Biological Significance: The SN5c monoclonal antibody recognizes human CD10, which is a 100 kDa, type II cell surface glycoprotein originally identified for its expression on most acute lymphoblastic leukemias. Subsequently, CD10 was shown to be the same molecule as neutral endopeptidase, or KII-NA. CD10 is a Zn2+-dependent metallopeptidase acting on substrates such as endothelin, glucagon, gastrin, neurotensin and bradykinin. CD10 is involved in the regulation of chemotactic and inflammatory processes involving neutrophils. In B cells, CD10 regulates stromal cell-dependent B lymphopoiesis and its expression has been reported on mature germinal center B cells. CD10 expression is also found on normal donor granulocytes and bone marrow stromal cells. Most likely, CB-CALLA and SN5c see different epitopes due to their ability to co-stain. Tag/Conjugate: PE. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD10 are readily searchable from our website. Different antibodies against the same target such as CD10 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.