anti-CD105 antibody product blog
Tags: Antibody; Monoclonal Antibody; CD105; anti-CD105 antibody;
The CD105 n/a (Catalog #MBS476177) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-CD105 Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CD105 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS).WB: 1:500-1:2000
ICC: 1:200-1:1000
IHC: 1:200-1:1000
FC: 1:200-1:400. Researchers should empirically determine the suitability of the CD105 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-CD105 Mouse mAb with the following immunoassay(s):
Western Blot (WB) (Western blot analysis using CD105 mAb against HEK293 (1) and CD105 (AA)
Immunofluorescence (IF) (Immunofluorescence analysis of HepG2 cells using CD105 mouse mAb (green). Blue)
Flow Cytometry (FC/FACS) (Flow cytometric analysis of HepG2 cells using CD105 mouse mAb (green) and negative control (purple).)
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded kidney cancer tissues (left) and stomach cancer tissues (right) using CD105 mouse mAb with DAB staining.)
Entrez Summary: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia.
Immunogen: Purified recombinant fragment of human CD105 expressed in E Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD105 are readily searchable from our website. Different antibodies against the same target such as CD105 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.