anti-CD11a antibody product blog
Tags: Antibody; Monoclonal Antibody; CD11a; anti-CD11a antibody;
The CD11a n/a (Catalog #MBS520031) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti-Rat CD11a Purified (Clone WT.1) (mouse IgG2a) reacts with Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s CD11a can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Flow Cytometry (FC), Immunoprecipitation (IP), Functional Assay (FA). Researchers should empirically determine the suitability of the CD11a n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-Rat CD11a Purified (Clone WT.1) (mouse IgG2a) with the following immunoassay(s):
Testing Data
LFA-1 (lymphocyte function associated molecule-1) is one of the leukocyte integrins. It is a heterodimer consisting of an and b subunits of 160-170 kDa and 95-100 kDa respectively. LFA-1 promotes non-antigen dependent adhesion of T-cells to a variety of lymphoid cells that bear its complementary receptor I-CAM-1 (1). It has a broad distribution and is found on most common lymphocytes. MBS520031 is specific for the a subunit of LFA-1. It inhibits homeotypic aggregation of PHA blasts and blocks the binding of rat lymphocytes to purified rat ICAM-1 (1). Applications include immunoprecipitation, flow cytometric analysis, immunohistochemistry (frozen), and functional testing.
Immunogen: Rat Splenic PHA blasts
Donor: BALB/c spleen
Fusion Partner: Mouse myeloma cell line PAI. Presentation: 200ug, purified Ig fraction in PBS containing 0.1% sodium azide (NaN3). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD11a are readily searchable from our website. Different antibodies against the same target such as CD11a may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.