|The CD14 cd14 (Catalog #MBS2533984) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti-Mouse CD14 Antibody (FITC conjugated) reacts with Mouse and may cross-react with other species as described in the data sheet.
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used <= 0.5 ug /106 cells in 100 ul). Since applications vary, the appropriate dilutions must be determined for individual use. Researchers should empirically determine the suitability of the CD14 cd14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD14 cd14 product has the following accession number(s) (GI #2274810) (NCBI Accession #BAA21517.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-Mouse CD14 Antibody (FITC conjugated) with the following immunoassay(s):
Testing Data (Thioglycolate-elicited Balb/c mouse peritoneal macrophages stained FITC anti-mouse CD14)
CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.
Conjugation: FITC. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD14 are readily searchable from our website. Different antibodies against the same target such as CD14 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CD14 also interacts with the following gene(s): CD180, CD36, ITGAM, ITGB2, LBP, LY96, TICAM2, TLR2, TLR4, TLR6. Asthma, Atherosclerosis, Cardiovascular Diseases, Fibrosis, Heart Diseases, Inflammation, Kidney Diseases, Liver Diseases, Lung Diseases, Necrosis are some of the diseases may be linked to Anti-Mouse CD14 Antibody (FITC conjugated). Adipose Tissue, Blood, Brain, Intestine, Kidney, Liver, Muscle, Ovary, Reticulum, Uterus tissues are correlated with this protein. The following patways have been known to be associated with this gene.