anti-CD15, Granulocytes antibody product blog
Tags: Antibody; Monoclonal Antibody; CD15, Granulocytes; anti-CD15, Granulocytes antibody;
The CD15, Granulocytes n/a (Catalog #MBS633035) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD15, Granulocytes (Lewis x, Le x, Hematopoietic Differentiation Antigen, SSEA-1, Stage-speci?c Embryonic Antigen, X Hapten, 3-fucosyl-N-acetyllactosamine, 3-FAL) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CD15, Granulocytes can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS).May be used for enumerating mature granulocytes in peripheral blood in Flow Cytometry.
Dilution: Flow Cytometry: 1ug to stain 1x10e6 cells. Researchers should empirically determine the suitability of the CD15, Granulocytes n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
This is a hematopoietic differentiation antigen (also named SSEA-1, stage-speci c embryonic antigen) expressed on most terminally differentiated myeloid cells including granulocytes, monocytes, eosinophils, mast cells, macrophages and Langerhans cells.On progenitor cells CD15 is coexpressed by 0.25 to 1% of bone marrow CD34+ cells.(2) In the peripheral blood growth factor mobilized CD34+ cells expressed CD15
CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin\'s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.
This antibody has been assigned to the CD15 cluster of differentiation at the Vth International Workshop on Human Leukocyte Differentiation Antigens in Boston (1993).
Immunogen: CD15 antigen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD15, Granulocytes are readily searchable from our website. Different antibodies against the same target such as CD15, Granulocytes may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.