|The CD154 n/a (Catalog #MBS531390) is an Antibody produced from Hamster and is intended for research purposes only. The product is available for immediate purchase. The CD154 antibody (biotin) reacts with Murine CD154 and may cross-react with other species as described in the data sheet. MyBioSource\'s CD154 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the CD154 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
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Hamster monoclonal CD154 antibody (biotin).
Biological Significance: CD154, also called CD40 ligand or CD40L, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In general, CD40L plays the role of a costimulatory molecule and induces activation in APC in association with T cell receptor stimulation by MHC molecules on the APC. Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen: CD154 antibody (biotin) was raised in hamster using activated murine Th1 clone D1.6 as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD154 are readily searchable from our website. Different antibodies against the same target such as CD154 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.