|The CD16/CD32 fcgr3 (Catalog #MBS845984) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-CD16/CD32; Rat IgG2b Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s CD16/CD32 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS); Immunofluorescence (IF); Immunoprecipitation (IP); Immunohistochemistry (IHC); Block. Researchers should empirically determine the suitability of the CD16/CD32 fcgr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD16/CD32 fcgr3 product has the following accession number(s) (GI #119877) (NCBI Accession #P08508.1) (Uniprot Accession #P08508). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Recombinant monoclonal antibody to CD16/CD32. Manufactured using recombinant technology with variable regions (i.e. specificity) from the hybridoma 2.4G2. This antibody binds murine Fc Receptors CD16/CD32 and inhibits binding of antibodies to these. It can therefore be used as an Fc-blocking reagent; to reduce non-specific staining of cells by antibodies binding via their Fc-region.
Immunogen: Mouse BALB/c Macrophage J774 Cell Line. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD16/CD32 are readily searchable from our website. Different antibodies against the same target such as CD16/CD32 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CD16/CD32 also interacts with the following gene(s): Fcer1g, Fcgr1, Fcgr2b, Fgr, Hck, Lyn, Plcg2, Syk, Vav1. Blood, Bone, Bone Marrow, Brain, Kidney, Liver, Lung, Muscle, Skin, Spleen tissues are correlated with this protein. The following patways have been known to be associated with this gene.