anti-CD20 antibody product blog
Tags: Antibody; Monoclonal Antibody; CD20; anti-CD20 antibody;
The CD20 krt20 (Catalog #MBS9400046) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD20 Mouse Monoclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s CD20 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P).Immunohistochemistry: 1:200. Researchers should empirically determine the suitability of the CD20 krt20 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD20 krt20 product has the following accession number(s) (GI #27894337) (NCBI Accession #NP_061883.1) (Uniprot Accession #P35900). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CD20 Mouse Monoclonal Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (IHC staining of paraffin-embedded Human tonsil tissue with CD20 mouse mAb �2F4 �diluted at 1:200.)
CD20 is a non glycosylated protein with a molecular weight of 35 or 37 kDa depending on the degree of phosphorylation. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca2+ channel subunit.
In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD20 are readily searchable from our website. Different antibodies against the same target such as CD20 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CD20 also interacts with the following gene(s): MKI67, MUC2, SLC4A3. Adenocarcinoma, Breast Neoplasms, Carcinoma, Colonic Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Stomach Neoplasms, Urinary Bladder Neoplasms are some of the diseases may be linked to CD20 Mouse Monoclonal Antibody. Brain, Intestine, Kidney, Muscle, Stomach tissues are correlated with this protein.