anti-CD3 epsilon antibody product blog
Tags: Antibody; Monoclonal Antibody; CD3 Epsilon; anti-CD3 epsilon antibody;
The CD3 epsilon cd3e (Catalog #MBS767691) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD3 epsilon Mouse Monoclonal reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CD3 epsilon can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC/FACS).WB: 1:2000 - 1:20000
IHC: 1:1000 - 1:10000
IF: 1:50 - 500. Researchers should empirically determine the suitability of the CD3 epsilon cd3e for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD3 epsilon cd3e product has the following accession number(s) (GI #163918) (NCBI Accession #AAA30834.1) (Uniprot Accession #P07766). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CD3 epsilon Mouse Monoclonal with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using MBS767691 (CD3E Antibody) at dilution of 1:8000)
Western Blot (WB) (Jurkat cells were subjected to SDS PAGE followed by western blot with MBS767691 (CD3E Antibody) at dilution of 1:10000)
CD3 is a complex of proteins that directly associates with the T cell receptor (TCR). The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells. This anti-CD3 is a monoclonal antibody directed against the epsilon chain of human CD3 molecule.
Immunogen: CD3e molecule, epsilon (CD3-TCR complex). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD3 epsilon are readily searchable from our website. Different antibodies against the same target such as CD3 epsilon may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.