|The CD33 cd33 (Catalog #MBS2543171) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Human CD33 Monoclonal Antibody (PerCP/Cy5.5 Conjugated) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CD33 can be used in a range of immunoassay formats including, but not limited to, Flow Cyometry (FC/FACS).
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used from 20 uL to 5 uL per 100 uL of peripheral blood. Please check your vial). Since applications vary, the appropriate dilutions must be determined for individual use. Researchers should empirically determine the suitability of the CD33 cd33 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD33 cd33 product has the following accession number(s) (GI #1032656012). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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CD33 is a 67 kD type I transmembrane glycoprotein also known as Siglec-3, gp67, and p67. It is a sialoadhesion immunoglobulin superfamily member expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. CD33 is absent on normal platelets, lymphocytes, erythrocytes and hematopoietic stem cells. CD33 functions as a sialic acid-dependent cell adhesion molecule with carbohydrate/lectin binding activity.
Buffer: PBS pH 7.2, 0.09% NaN3, 0.2% BSA. Conjugation: PerCP/Cy5.5. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD33 are readily searchable from our website. Different antibodies against the same target such as CD33 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CD33 also interacts with the following gene(s): ANPEP, CD19, CD2, CD34, CD7, CEBPA, FUT4, NCAM1, PTPN11. The following patways have been known to be associated with this gene. Blood, Bone, Bone Marrow, Brain, Kidney, Liver, Lung, Lymph Node, Prostate, Thymus tissues are correlated with this protein. Alzheimer Disease, Breast Neoplasms, Cardiovascular Diseases, Cell Transformation, Neoplastic, Death, Inflammation, Leukemia, Myeloid, Acute, Lung Diseases, Necrosis, Respiratory Tract Diseases are some of the diseases may be linked to Anti-Human CD33 Monoclonal Antibody (PerCP/Cy5.5 Conjugated).