anti-CD37 antibody product blog
Tags: Antibody; Monoclonal Antibody; CD37; anti-CD37 antibody;
The CD37 cd37 (Catalog #MBS9602482) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD37 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s CD37 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA).ELISA: 1:10000
ICC: 1:200-1:1000. Researchers should empirically determine the suitability of the CD37 cd37 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD37 cd37 product has the following accession number(s) (GI #91807110) (NCBI Accession #NP_001035120.1) (Uniprot Accession #P11049). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CD37 Antibody with the following immunoassay(s):
Immunofluorescence (IF) (Figure 1: Confocal immunofluorescence analysis of methanol-fixed BCBL-1 (left) and L1210 (right) cells using CD37 mouse mAb(green), showing membrane localization. Blue: DRAQ5 fluorescent DNA dye.)
Description: CD37, also known as GP52-40, TSPAN26, MGC120234. Enterz Protein NP_001035120. It is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.
Subunit Structure: Interacts with SCIMP.
Similarity: Belongs to the tetraspanin (TM4SF) family.
Immunogen: Purified recombinant fragment of human CD37 expressed in E. Coli
Subcellular Location: Membrane.
Tissue Specificity: B-lymphocytes. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD37 are readily searchable from our website. Different antibodies against the same target such as CD37 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CD37 also interacts with the following gene(s): CD22, LYN, SYK, UPK1B. Blood, Bone, Bone Marrow, Lung, Lymph, Lymph Node, Pharynx, Spleen, Thymus, Vascular tissues are correlated with this protein. Breast Neoplasms, Carcinoma, Cardiovascular Diseases, Disease Models, Animal, Edema, Immune System Diseases, Inflammation, Kidney Diseases, Necrosis, Skin Neoplasms are some of the diseases may be linked to CD37 Antibody.