anti-CD3e antibody product blog
Tags: Antibody; Monoclonal Antibody; CD3E; anti-CD3E antibody;
The CD3e cd3e (Catalog #MBS4151549) is an Antibody produced from Armenian Hamster and is intended for research purposes only. The product is available for immediate purchase. The Anti-Mouse CD3e-R-PE Conjugate Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s CD3e can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the CD3e cd3e for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The CD3e cd3e product has the following accession number(s) (GI #119587768) (NCBI Accession #EAW67364.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-Mouse CD3e-R-PE Conjugate Antibody with the following immunoassay(s):
Testing Data
CD3epsilon, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The 145-2C11 monoclonal antibody recognizes an epitope on the 25kD epsilon chain of the CD3/TCR complex. In the presence of Fc receptor-bearing accessory cells, soluble 145-2C11 can activate primed and naive T cell in vitro. 145-2C11 can also induce redirected lysis of specific target cells by CTL clones and it can block lysis of specific target cells by antigen-specific CTLs. Immobilized 145-2C11 can activate both normal T lymphocytes and cloned T cell lines.
Immunogen: H-2Kb-specific mouse cytotoxic T lymphocyte clone BM10-37
Storage Buffer: PBS, pH 7.4 with 0.05% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD3e are readily searchable from our website. Different antibodies against the same target such as CD3e may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Brain, Heart, Intestine, Kidney, Liver, Lung, Lymph Node, Spleen, Thymus tissues are correlated with this protein. Arthritis, Rheumatoid, Carcinoma, Cell Transformation, Neoplastic, Disease Models, Animal, Immunologic Deficiency Syndromes, Inflammation, Lung Diseases, Necrosis, Severe Combined Immunodeficiency, Vascular Diseases are some of the diseases may be linked to Anti-Mouse CD3e-R-PE Conjugate Antibody.