|The CD4 cd4 (Catalog #MBS2533843) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti-Mouse CD4 Antibody (APC conjugated) reacts with Mouse and may cross-react with other species as described in the data sheet.
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used <= 0.5 ug /106 cells in 100 ul). Since applications vary, the appropriate dilutions must be determined for individual use. Researchers should empirically determine the suitability of the CD4 cd4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD4 cd4 product has the following accession number(s) (GI #3947700) (NCBI Accession #CAA60883.1) (Uniprot Accession #Q13969). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-Mouse CD4 Antibody (APC conjugated) with the following immunoassay(s):
Testing Data (C57BL/6 mouse splenocytes stained with FITC anti-mouse CD3 and APC anti-mouse CD4)
CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck.
Conjugation: APC. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD4 are readily searchable from our website. Different antibodies against the same target such as CD4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Bone, Bone Marrow, Brain, Intestine, Liver, Lung, Lymph Node, Spleen, Thymus tissues are correlated with this protein. CD4 also interacts with the following gene(s): CCR5, CD2, CD38, CD69, CD8A, FOXP3, IL2RA, LCK, PTPRC.