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anti-CD40 antibody product blog

Posted on 2015-12-25 00:50:59 by mybiosource_staff
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Tags: Antibody; Monoclonal Antibody; CD40; anti-CD40 antibody;
The CD40 cd40 (Catalog #MBS531964) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The CD40 antibody reacts with Murine and may cross-react with other species as described in the data sheet. MyBioSource\'s CD40 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the CD40 cd40 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The CD40 cd40 product has the following accession number(s) (GI #114053977) (NCBI Accession #ABI49511.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Rat monoclonal CD40 antibody.

CD40 cd40

Biological Significance: CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. Deficiency can cause Hyper-IgM syndrome type 3. Immunogen: CD40 antibody was raised in rat using CD40 as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD40 are readily searchable from our website. Different antibodies against the same target such as CD40 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Arthritis, Rheumatoid, Atherosclerosis, Cardiovascular Diseases, Disease Models, Animal, Heart Diseases, Inflammation, Liver Diseases, Lung Diseases, Necrosis, Neoplasms, Experimental are some of the diseases may be linked to CD40 antibody. CD40 also interacts with the following gene(s): BIRC2, BIRC3, CD40LG, JAK3, NFKB1, TRAF1, TRAF2, TRAF3, TRAF5, TRAF6. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Kidney, Liver, Lung, Lymph, Lymph Node, Skin, Tonsil tissues are correlated with this protein.
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