anti-CD41 antibody product blog
Tags: Antibody; Monoclonal Antibody; CD41; anti-CD41 antibody;
The CD41 itga2b (Catalog #MBS2548880) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD41 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CD41 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin (IHC-p).IHC: 1:100. Researchers should empirically determine the suitability of the CD41 itga2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD41 itga2b product has the following accession number(s) (GI #88758615) (NCBI Accession #NP_000410.2) (Uniprot Accession #P08514). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CD41 Monoclonal Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human breast cancer tissue using CD41 Monoclonal Antibody at dilution of 1:200.)
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Immunogen: Synthetic Peptide
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.4
Conjugation: Unconjugated. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD41 are readily searchable from our website. Different antibodies against the same target such as CD41 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone Marrow, Brain, Embryonic Tissue, Liver, Placenta, Spleen, Thymus tissues are correlated with this protein. CD41 also interacts with the following gene(s): COL2A1, FGA, FGG, FN1, ITGB3, PTK2, SYK. Atherosclerosis, Cardiovascular Diseases, Hemorrhage, Myocardial Infarction, Myocardial Ischemia, Nervous System Diseases, Stroke, Thrombasthenia, Thrombocytopenia, Thrombosis are some of the diseases may be linked to CD41 Monoclonal Antibody. The following patways have been known to be associated with this gene.