|The CD57 b3gat1 (Catalog #MBS179031) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-human CD57 Antibody FITC Conjugated, Flow Validated reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CD57 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the CD57 b3gat1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD57 b3gat1 product has the following accession number(s) (GI #77695914) (NCBI Accession #NP_061114.2) (Uniprot Accession #Q9P2W7). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-human CD57 Antibody FITC Conjugated, Flow Validated with the following immunoassay(s):
Testing Data (Lymphocytes gated PBMCs were stained withmouse anti-human CD57 FITC (clone HNK-1) alongwith mouse anti-human CD3 APC (right panel).Lymphocytes gated PBMCs were stained withmouse IgM isotype control FITC along with mouseanti-human CD3 APC (left panel) )
Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo- orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl- sphingomyelin was the most effective, followed by palmitoyl- sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).
Subcellular Localization: Golgi apparatus membrane; Single-pass type II membrane protein.
Tissue Specificity: Mainly expressed in the brain. Sensitivity: 5ul per sample
Contents: PBS, pH7.2, 0.09% NaN3 and 0.2% (w/v) BSA. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD57 are readily searchable from our website. Different antibodies against the same target such as CD57 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Brain, Nerve tissues are correlated with this protein. Congenital Abnormalities, Necrosis, Prenatal Exposure Delayed Effects, Prenatal Injuries are some of the diseases may be linked to Anti-human CD57 Antibody FITC Conjugated, Flow Validated.