|The CD68 cd68 (Catalog #MBS2541861) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD68 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CD68 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC).
IHC: 1:50-1:500. Researchers should empirically determine the suitability of the CD68 cd68 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD68 cd68 product has the following accession number(s) (GI #298665). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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CD68 is a type I transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It belongs to the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. CD68 is also a member of the scavenger receptor family. It may play a role in phagocytic activities of tissue macrophages.
Immunogen: CD68 fusion protein Ag22815
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD68 are readily searchable from our website. Different antibodies against the same target such as CD68 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CD68 also interacts with the following gene(s): CD163, CD34, CD36, CD8A, EMR1, EMR2, ITGAM, ITGAX, PTPRC. Adenocarcinoma, Atherosclerosis, Cardiovascular Diseases, Disease Models, Animal, Fibrosis, Inflammation, Kidney Diseases, Liver Diseases, Lung Diseases, Necrosis are some of the diseases may be linked to CD68 Antibody. Blood, Bone, Brain, Kidney, Liver, Lung, Lymph Node, Muscle, Skin, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene.