anti-CD68 antibody product blog
Tags: Antibody; Monoclonal Antibody; CD68; anti-CD68 antibody;
The CD68 cd68 (Catalog #MBS668303) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Monoclonal Antibody to CD68 (Clone: ABM53F5)-FITC Conjugated reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CD68 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS).Flow Cytometry: 0.5-1 ug/10^6 cells. Researchers should empirically determine the suitability of the CD68 cd68 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD68 cd68 product has the following accession number(s) (GI #147744552) (NCBI Accession #P34810.2) (Uniprot Accession #P34810). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Monoclonal Antibody to CD68 (Clone: ABM53F5)-FITC Conjugated with the following immunoassay(s):
Flow Cytometry (FC/FACS) (Fig: 1- Cell surface Flow analysis of hCD68 in human PBMC (Monocytes) using 0.5 ?g/ 10^6 cells. Green represents isotype control ;red represents anti-hCD68 FITC conjugated antibody.)
CD68 is a transmembrane glycoprotein which acts as a commercialized marker for human monocytes and macrophages. Its expression is thought to be regulated by a macrophage-specific promoter. However, several immunohistochemical studies have indicated that CD68 antibodies also react with other haematopoietic and non-haematopoietic cell types. It also can stain myeloid cells, dendritic cells, fibroblasts, Langerhans cells and others. In human monocytes, which produce high levels of CD68 mRNA, the gene is characterized by intramolecular ligations between the promoter and the 3\'intervening region. CD68 is also used as a pan-macrophage marker for TAM (Tumor-Associated Macrophages) which always involve in carcinogenesis.
Immunogen Information: A partial length recombinant protein (a.a 80-280) of CD68 was used as the immunogen for this antibody. Antigen: CD68
Conjugate: FITC. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD68 are readily searchable from our website. Different antibodies against the same target such as CD68 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CD68 also interacts with the following gene(s): CD163, CSF1R, PSMD7, TYROBP. Adenocarcinoma, Atherosclerosis, Cardiovascular Diseases, Disease Models, Animal, Fibrosis, Inflammation, Kidney Diseases, Lung Diseases, Necrosis, Nervous System Diseases are some of the diseases may be linked to Monoclonal Antibody to CD68 (Clone: ABM53F5)-FITC Conjugated.