|The CD68 cd68 (Catalog #MBS9200304) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD68 Antibody (Ascites) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CD68 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).
WB~~1:1000~4000. Researchers should empirically determine the suitability of the CD68 cd68 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD68 cd68 product has the following accession number(s) (GI #91199550) (NCBI Accession #NP_001035148.1) (Uniprot Accession #P34810). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CD68 Antibody (Ascites) with the following immunoassay(s):
Western Blot (WB) (CD68 Antibody western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the CD68/CD68 (kpi) antibody detected the CD68/CD68 (kpi) protein (arrow).)
This gene encodes a 110-kD transmembrane glycoprotein that
is highly expressed by human monocytes and tissue macrophages. It
is a member of the lysosomal/endosomal-associated membrane
glycoprotein (LAMP) family. The protein primarily localizes to
lysosomes and endosomes with a smaller fraction circulating to the
cell surface. It is a type I integral membrane protein with a
heavily glycosylated extracellular domain and binds to tissue- and
organ-specific lectins or selectins. The protein is also a member
of the scavenger receptor family. Scavenger receptors typically
function to clear cellular debris, promote phagocytosis, and
mediate the recruitment and activation of macrophages. Alternative
splicing results in multiple transcripts encoding different
Antigen Type: Synthetic Peptide. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD68 are readily searchable from our website. Different antibodies against the same target such as CD68 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CD68 also interacts with the following gene(s): CD163, CD34, CD36, CD8A, EMR1, EMR2, ITGAM, ITGAX, PTPRC. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Kidney, Liver, Lung, Lymph Node, Muscle, Skin, Vascular tissues are correlated with this protein. Adenocarcinoma, Atherosclerosis, Cardiovascular Diseases, Disease Models, Animal, Fibrosis, Inflammation, Kidney Diseases, Liver Diseases, Lung Diseases, Necrosis are some of the diseases may be linked to CD68 Antibody (Ascites).