anti-CDH3 antibody product blog
Tags: Antibody; Monoclonal Antibody; CDH3; anti-CDH3 antibody; CDH3/P-Cadherin;
The CDH3 cdh3 (Catalog #MBS2401628) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-CDH3/P-Cadherin Antibody (clone 2D5) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CDH3/P-Cadherin can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Western Blot (WB).IF: 1:100
IHC-P: 10 ug/ml
WB: 1:4000. Researchers should empirically determine the suitability of the CDH3 cdh3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CDH3 cdh3 product has the following accession number(s) (GI #14589891) (NCBI Accession #NP_001784.2) (Uniprot Accession #P22223). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-CDH3/P-Cadherin Antibody (clone 2D5) with the following immunoassay(s):
Immunohistochemistry (IHC) (Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunofluorescence (IF) (Immunofluorescent staining of HeLa cells using anti-CDH3 mouse monoclonal antibody.)
Immunofluorescence (IF) (Anti-CDH3 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CDH3.)
Western Blot (WB) (HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDH3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDH3.)
P-Cadherin is a classical cadherin from the cadherin superfamily. the encoded protein is a calcium-dependent cell-cell adhesion glycoproteincomprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in asix-cadherin cluster in a region on the long arm of chromosome 16 thatis involved in loss of heterozygosity events in breast and prostatecancer.
Immunogen: Full length human Recombinant protein of human CDH3(NP_001784) produced in HEK293T cell.
Conjugation: Unconjugated. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CDH3 are readily searchable from our website. Different antibodies against the same target such as CDH3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. CDH3 also interacts with the following gene(s): CTNNB1. Adenoma, Breast Neoplasms, Colorectal Neoplasms, Ectodermal dysplasia, ectrodactyly, and macular dystrophy, Gastrointestinal Diseases, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms, Experimental, Skin Diseases are some of the diseases may be linked to Anti-CDH3/P-Cadherin Antibody (clone 2D5).