|The CDK1 cdk1 (Catalog #MBS245328) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone POH-1] to Human CDK1 / CDC2 reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CDK1 / CDC2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB).
IHC-P (20 ug/ml), WB
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the CDK1 cdk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CDK1 cdk1 product has the following accession number(s) (GI #4502709) (NCBI Accession #NP_001777.1) (Uniprot Accession #P06493). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Mouse Monoclonal [clone POH-1] to Human CDK1 / CDC2 with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-Cdc2 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.)
CDC2/CDK1, a CDC2/CDK -type protein kinase, regulates cell cycle transitions G1 to S and G2 to M. CDC2/CDK1 is maintained in an inactive state by phosphorylation by kinases MYT1 and WEE1. The active kinase, called the M-phase promoting factor, consists of a heterodimer with cyclin B, and final activation at G2/M results from CDC25 phosphatase-mediated dephosphorylation of CDC2/CDK1.
Target Species: Human
Immunogen Description: Recombinant full-length human cdc2. Immunogen Type: Recombinant protein
Immunogen: CDK1 / CDC2 antibody was raised against recombinant full-length human cdc2. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CDK1 are readily searchable from our website. Different antibodies against the same target such as CDK1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Kidney, Liver, Lung, Muscle, Prostate, Skin, Vascular tissues are correlated with this protein. CDK1 also interacts with the following gene(s): BIRC5, BUB1, BUB1B, CCNA1, CCNA2, CCNB1, CCNB2, CDC25C, CDC6, RRM2.